Aprobarbitone is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. Aprobarbitone was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. Aprobarbitone (like all barbiturates) works by binding to the GABAA receptor at either the alpha or the beta sub unit.
Aprobarbitone is used in the treatment of:
• Sleep Initiation and Maintenance Disorders
• Stomach upset
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